AMPEL BioSolutions is a company founded to bring personalized precision medicine to patients, especially those suffering from autoimmune and inflammatory diseases. The AMPEL team brings their expertise in basic and translational research, clinical trial design, and bioinformatics together in a new way to develop scalable systems using AI and deep machine learning to improve patient outcomes. To give patients and their doctors the tools and information necessary to make decisions based on that individual’s genomic profile.

In 2023, AMPEL expects to commercialize its first product, a CLIA-certified blood test for patients/physicians called LuGENE® that assesses disease state/flares and best drug option(s). Watch the video below to hear Dr. Grammer explain LuGENE®.

 

AMPEL in the News

UVAToday: Q&A UVA-Trained Biotech Leader Setting her Sights on Lupus

Bloomberg Markets Radio Program: Personalized Precision Medicine

NBC12: Digital Dialogue Lupus Awareness Month on LuGENE® for Lupus

NPR: New Test May Guide Treatment of Common Skin Diseases on DermaGENE® for Lupus, Psoriasis, Atopic Dermatits and Scleroderma

CBS19: Coverage of CovGENE® to predict COVID patients who may experience severs disease

 

Current UVA Intern

Julianna Hitchcock

 

Julianna Hitchcock

UVA Student and AMPEL Intern, June 2022-present.     
Rodman Scholar, BS BME with a minor in Computer Science, expected May 2024.

Company Industry
Biotech & Life Sciences
Company Type
Private
Company Size
10-50 Employees
Alumni Spotlight

Erika Hubbard

Erika Hubbard
Bioengineering and Biomedical Engineering
2017
School of Engineering & Applied Science

Bioinformatics and Machine Learning Scientist, June 2016-August 2021
PhD Health and Biomedical Data Science Student jointly with AMPEL and George Washington University, August 2021-present
Publications with AMPEL :
Transcriptomics data: pointing the way to subclassification and personalized medicine in systemic lupus erythematosus 
Analysis of gene expression from systemic lupus erythematosus synovium reveals myeloid cell-driven pathogenesis of lupus arthritis

Sophia Kerns

Sophia Kerns
Biomedical Engineering
2022
School of Engineering & Applied Science

Research Associate, March 2021-present
Biomedical Engineering UVA Capstone with AMPEL, August 2021-May 2022
UVA B.S. BME May 2022, Full time after graduation

Kathryn Kingsmore Allison PhD

Kathryn Kingsmore Allison PhD
Biomedical Engineering PhD 
2018
School of Engineering & Applied Science

Biomedical Engineering PhD 
Staff Scientist and Medical Affairs Liason, September 2020-present
Bioinformatics & Machine Learning Post-Doc, September 2018-September 2020
Publications with AMPEL: 
Machine learning reveals distinct gene signature profiles in lesional and nonlesional regions of inflammatory skin diseases
An introduction to machine learning and analysis of its use in rheumatic diseases

Emily Leventhal

Emily Leventhal
BS Computer Science
2022
School of Engineering & Applied Science

Research Associate, June 2022-present

Adam Labonte

PhD Immunology
2016
School of Medicine

Staff Scientist and Medical Affairs Liason, AMPEL BioSolutions, June 2018-present.         
             UVA BA Biology 2010, MS Microbiology 2012, PhD Immunology 2016.
             AMPEL BioSolutions Systems Immunology Post-Doc June 2016-June 2018.

 

Publications with AMPEL:

A.C. Labonte, B. Kegerreis, N. Geraci, P. Bachali, S. Madamanchi, R. Robl, M.D. Catalina, P.E. Lipsky and A.C. Grammer. “Identification of alterations in macrophage polarization associated with disease activity in systemic lupus erythematosus,” PLoS One 13(12):e0208132, 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478921/
 
M.D. Catalina, K.A. Owen, A.C. Labonte, A.C. Grammer and P.E. Lipsky, “The pathogenesis of systemic  lupus erythematosus: harnessing Big Data to understand the molecular basis of lupus,” J. Autoimmunity 110:102359-102369, 2020.  https://pubmed.ncbi.nlm.nih.gov/31806421/
 
K.A. Owen, A. Price, H. Ainsworth, B.N. Aidukaitis, P. Bachali, M.D. Catalina, J.M. Dittman, T.D. Howard, Kathryn M. Kingsmore, A.C. Labonte, Robert D. Robl, Kip D. Zimmerman, C.D. Langefeld, P.E. Lipsky* and A.C. Grammer* (*co-corresponding authors),“Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries,” Am. J. Human Genetics 107:1-18, 2020.  https://doi.org/10.1016/j.ajhg.2020.09.007
 

Claire Dykas

B.A. Biology
2017
School of Arts and Sciences

Medical Affairs Liaison and Clinical Trial Operations, 2017-present.